Serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase variations with their Pearson’s coefficient correlation in sickle cell disease

Background: The sickle cell disease condition with hepatic dysfunction shows the abnormal variations in liver function tests including serum aminotransferases enzymes like glutamic oxaloacetic transaminase (SGOT) and pyruvic (SGPT) levels were changed to discuss their significance disease. Objectives: Studied of SGOT SGPT level variation disease, Pearson’s correlation coefficient SGOT& Material methods: This study was conducted Department Biochemistry, People’s College Medical Sciences Research Centre for Scientific Development (CSRD), University, Bhopal. estimated by Reitman & Frankel’s method diagnosed. Results: In present study, mean standard deviation cases vs. controls showed significant difference it calculated using SPSS software version-24. ± SD vs found 69.98 69.31; 25.17± 5.25 65.28 60.07; 22.72 5.47 respectively. P˂0.000 be statistically highly significant. Correlation positive between enzymes. Conclusion: transaminases significantly increased so could another clinical bio-marker diagnosis Keywords: SGOT; SGPT; correlation;